|
KMID : 1147820180070020063
|
|
Journal of Naturopathy
2018 Volume.7 No. 2 p.63 ~ p.69
|
|
|
Research on the Bacillus-fermented Enzamin Administration on Human NK Cell Activity and Bone Density of Hamster : A Pilot Study
|
|
Ryu Seo-Won
Tokio Fujii
Lee Hyung-Hoan
|
|
|
Abstract
|
|
|
Purpose: The purpose of this study was to investigate the effects of Bacillus fermentation broth (ENM) on the human NK cell activity, and bone matrix density, matrix content and area of hamsters fed ENM.
Methods: NK cell activity was tested, and bone mineral density were measured by x-ray.
Results: NK cell activity was significantly higher in the control group (644.71 pg/ml) and in the test group (1796.37 pg/ml) (p<.004). Test groups were significantly increased by 1110.37 pg/ml in the pre-test and 1796.37 pg/ml in the post-test(p<.001). Behavioral observations after feeding ENM to hamsters showed normal behavior with no difference between control and test groups. The hamster body weight of the control was 106 g at the initial and final 27 days. In the test group, the initial weight was 96.6 g and the final 27 days was 114 g. No morphological changes were observed in the X-ray photographs of the hamster hind legs. The bone matrix density was 0.059 g/cm3 in control and 0.062 g/cm3 in the test, which was increased by 0.003 g/ cm3. The bone matrix content was 0.175 g in the control and 0.196 g in the test. The bone area was 2.95 cm2 in the control and 3.19 cm2 in the test, which was increased by 0.19 cm2 . In the autopsy, neither the control nor the test group showed any remarkable abnormality, and each organ was normal.
Conclusions: It is thought that ingestion of ENM is useful for immunity enhancement.
|
|
|
KEYWORD
|
|
|
natural killer cell, hamster, Bacillus broth, fermentation, immunity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|